In vitro Evaluation of Anticancer Activity of the Methanolic and Aqueous Extracts of the Petals of C. tinctorius L. (Safflower Florets)

The anticancer activity of the methanolic and aqueous extracts of the petals of safflower florets were analyzed using breast cancer cell lines namely MCF-7. The, MCF-7 cells were incubated with increasing concentrations of the methanolic and aqueous extract of the petals ranging from 5-150ug/ml for different time periods (6, 12, 18, 24, 36, 48, 72) and the cell viability was analyzed using MTT assay, aqueous extract of safflower florets Manjira and SSf-658 was found to be potent cytotoxic (IC50 value 34.17,36.96µg/ml) as similar to standard drug cisplatin. In addition to methanol extract pbns-12 was found to be potent cytotoxic with IC50 value 47.401±3.991 respectively.