Explorations of object and location memory using fMRI

Passaro, Antony D. and Elmore, L. Caitlin and Ellmore, Timothy M. and Leising, Kenneth J. and Papanicolaou, Andrew C. and Wright, Anthony A. (2013) Explorations of object and location memory using fMRI. Frontiers in Behavioral Neuroscience, 7. ISSN 1662-5153

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Abstract

Content-specific sub-systems of visual working memory (VWM) have been explored in many neuroimaging studies with inconsistent findings and procedures across experiments. The present study employed functional magnetic resonance imaging (fMRI) and a change detection task using a high number of trials and matched stimulus displays across object and location change (what vs. where) conditions. Furthermore, individual task periods were studied independently across conditions to identify differences corresponding to each task period. Importantly, this combination of task controls has not previously been described in the fMRI literature. Composite results revealed differential frontoparietal activation during each task period. A separation of object and location conditions yielded a distributed system of dorsal and ventral streams during the encoding of information corresponding to bilateral inferior parietal lobule (IPL) and lingual gyrus activation, respectively. Differential activity was also shown during the maintenance of information in middle frontal structures bilaterally for objects and the right IPL and left insula for locations. Together, these results reflect a domain-specific dissociation spanning several cortices and task periods. Furthermore, differential activations suggest a general caudal-rostral separation corresponding to object and location memory, respectively.

Item Type: Article
Subjects: STM Open Library > Biological Science
Depositing User: Unnamed user with email support@stmopenlibrary.com
Date Deposited: 17 Mar 2023 06:38
Last Modified: 19 Mar 2024 04:15
URI: http://ebooks.netkumar1.in/id/eprint/898

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